Devon Jakob of the Xu Research Group

Graduate student Devon Jakob will present

"Direct Two-Photon Polymerization of Well-Defined Three-Dimensional Nanostructures"

 on September 26, 2017 at 4:10 PM in Neville Hall, Room 3.

The invention of femtosecond lasers has made the microfabrication of high detailed three-dimensional nanostructures achievable.1 By controlling the output of localized laser energy pulses, highly confined chemical reactions generating the polymerization of photosensitive resins leads to nanostructures with wide arrays of properties. Two major and practical benefits arise from this technique; the microfabrication is capable of producing three-dimensional structures with a spatial resolution of around 100-nm while the finished structures afford diversified mechanical and photonic properties due to their well-defined geometric architectures. These properties are of increasing interest across the fields of chemistry, material science, and biology.2-3
Recently, it has been shown that two-photon polymerization can be used to create easily functionalized, thermally and electrically conductive atomic force microscopy probes with tip radii of 25-nm and which are tailored to individual experiments.4 A separate group has recently presented a novel process in which two-photon polymerization is directly implemented in order to fabricate ultracompact (100-µm) multi-lens objectives for use in miniature optical systems such as fiber-imaging systems and quantum detectors.5 Microstructures produced through two-photon polymerization have also become a forefront in regenerative medicine. The high spatial resolution achievable by this technique has led to the development of various microscopic scaffolds capable of culturing and allowing for the differentiation of human bone marrow derived stem cells with far greater effectiveness than previous substrates.6
  1. S. Maruo, O. Nakamura, and S. Kawata. “Three-dimensional microfabrication with two-photon-absorbed photopolymerization. Optics Letters, Vol. 22, 132-134. (1997)
  2. S. Kawata, H. Sun, T. Tanaka, and K. Takada. “Finer features for functional microdevices” Nature 412, 697-698 (2001)
  3. J. Serbin, A. Egbert, A. Ostendord, B. N. Chichkov, R. Houbertz, G. Domann, J. Schulz, C. Cronauer, K. Fröhlich, and M. Popall. “Femtosecond laser-induced two-photon polymerization of inorganic-organic hybrid materials for applications in photonics” Optics Letters, Vol. 28, 301-303. (2003)
  4. G. Göring, P. Dietrich, M. Blaicher, S. Sharma, J. Korvink, T. Schimmel, C. Koos, and H. Hölscher.
  5. “Tailored probes for atomic force microscopy fabricated by two-photon polymerization” Applied Physics Letters: Vol 109, 063101 (2016)
  6. T. Gissibl, S. Thiele, A. Herkommer, and H. Giessen. “Two-photon direct laser writing of ultracompact multi-lens objectives” Nature Photonics 10, 554-560 (2016)
  7. M. Nava, N. Di Maggio, T. Zandrini, G. Cerullo, R. Osellame, I. Martin, M. Raimondi. “Synthetic niche substrates engineered via two-photon laser polymerization for the expansion of human mesenchymal stromal cells” J Tissue Eng Regen Med (2016)



Tuesday, September 26, 2017


Devon Jakob