Robert Flowers

Robert Flowers
Deputy Provost for Faculty Affairs
Danser Distinguished Faculty Chair
Professor
Seeley G. Mudd, Room 796
(610) 758-4048

Research Interests:

Organometallic reaction mechanisms, lanthanide chemistry, electrochemical studies of single electron transfer, calorimetry, protein refolding and renaturation, molecular recognition.

Teaching Interests:

Undergraduate organic chemistry, advanced courses in organic chemistry including: reaction mechanisms, reactive intermediates, physical organic chemistry, application of lanthanides in organic synthesis. 
 

Selected Recent Publications:

“Substituent Effects and Supramolecular Stabilization of Titanocene(III): Implications for Catalysis in Single Electron Steps” Gansäuer, A.; Kube, C.; Daasbjerg, K.; Sure, R.; Grimme, S.; Fianu, G.D.; Sadasivam, D.V.; Flowers, R.A., II J. Am. Chem. Soc. 2014, 136, 1663-1671. 99.

“Sm and Yb Reagents” Choquette, K.A.; Flowers, R.A., II in Comprehensive Organic Synthesis, 2nd Edition; Molander, G.A., Knochel, P., Eds.; Elsevier: Oxford, 2014; Vol. 1, pp. 279-343. Book Chapter 

“Solvent-Dependent Substrate Reduction by [Sm{N(SiMe3)2}2(THF)2]. An Alternative Approach for Accelerating the Rate of Substrate Reduction by Sm(II)” Chiuck, T.V.; Hilmersson, G.; Flowers, R.A., II J. Org. Chem. 2014, 79, 9441-9443. 

“Kinetic and Mechanistic Properties of fac-Ir(ppy)3-catalyzed Redox Neutral Coupling of Alkyl Halides and Arenes: The Fate of the Photocatalyst” Devery, J.J. III; Douglas, J.J.; Nguyen, J.D.; Cole, K.P.; Flowers, R.A. II; Stephenson, C.R.J. Chem. Sci. 2015, 6, 537-541. 

“Mechanistic Study of the Titanocene(III)-Catalyzed Radical Arylation of Epoxides” Gansäuer, A.; von Laufenberg, D.; Kube, C.; Dahmen, T.; Michelmann, A.; Behlendorf, M.; Sure, R.; Seddiqzai, M.; Grimme, S.; Fianu, G.D.; Sadasivam, D.V.; Flowers, R.A., II Chem. Eur. J. 2015, 21, 280-289. 

“Expedient and Highly Diastereoselective Synthesis of 2 (2- Hydroxyethyl)bicyclo[2.1.1]hexan-1-ols via Allylsamarium Bromide-Mediated Cascade Doublecyclization” Shen., M.; Tu, Y.; Xie, G.; Niu, Q.; Mao, H.; Xie, T.; Flowers, R.A., II; Lv, X.; Wang, X. J. Org. Chem. 2015, 80, 52-61. 

“Mechanistic Study of the Samarium Diiodide - N,N-dimethyl-2-aminoethanol Reducing System” Chciuk, T.V.; Boland, B.P.; Flowers, R.A., II Tetrahedron Letters 2015 (in press for a special issue in honor of Professor Harry Wasserman). 

“Titanocenium(III) Complexes for Catalysis in Single Electron Steps” Gansäuer, A.; Hildebrandt, S.; Michelmann, Dahmen, T.; von Laufenberg, D.; Fianu, G.D.; Flowers, R.A., II Angew. Chem. Int. Ed. 2015, in press.  Harry Wasserman). 

“Titanocenium(III) Complexes for Catalysis in Single Electron Steps” Gansäuer, A.; Hildebrandt, S.; Michelmann, Dahmen, T.; von Laufenberg, D.; Fianu, G.D.; Flowers, R.A., II Angew. Chem. Int. Ed. 2015, in press.